Caffeine inhibits protein synthesis:
https://pubmed.ncbi.nlm.nih.gov/28634643/
Caffeine increases blood coagulation factor:
https://journals.lww.com/acsm-msse/Fulltext/2019/03000/Caffeine_Augments_the_Prothrombotic_but_Not_the.5.aspx
Caffeine decreases insulin sensitivity in humans:
https://diabetesjournals.org/care/article/25/2/364/23352/Caffeine-Can-Decrease-Insulin-Sensitivity-in
Caffeine causes premature birth resulting in growth moronation and low birth weight:
https://pubmed.ncbi.nlm.nih.gov/3661529/
Caffeine increases risk of osteoporosis:
https://pubmed.ncbi.nlm.nih.gov/16758142/
Caffeine interferes with REM sleep:
https://pubmed.ncbi.nlm.nih.gov/34024173/
Caffeine increases risk of seizures:
https://pubmed.ncbi.nlm.nih.gov/29414557/
Caffeine Exacerbates Postictal Hypoxia:
https://www.sciencedirect.com/science/article/abs/pii/S0306452219306700
Caffeine induces panic attacks and anxiety:
https://pubmed.ncbi.nlm.nih.gov/34871964/
not seeing a downside for males at least
>Caffeine causes premature birth resulting in growth moronation and low birth weight:
>https://pubmed.ncbi.nlm.nih.gov/3661529/
>Decreases in mean birth weight were 6, 31, and 105 g
Wow, it's fricking nothing
>Wow, it's fricking nothing
No it's not. But everyone knows that pregnant women shouldn't drink for decades
>Caffeine increases risk of osteoporosis:
>https://pubmed.ncbi.nlm.nih.gov/16758142/
>The increased risk of fracture with both a high caffeine intake and coffee consumption was confined to women with a low calcium intake
This just in: lifting increases cancer mortality by .1% if you are a cancer patient that was diagnosed in october whose mother's maiden name is johnson.
>oh shit time to post on IST about how lifting is bad for you
kek, sums up the bulk of fear-mongering present on this board. Having public access to a bunch of studies is a blessing and a curse, because most people are too moronic to actually understand their results (and that includes journalists)
Did you even read these anon?
That’s why you should do lines of crack instead
lmao frick you OP cluster headaches are my free ticket to drink as much caffeine as I want whenever I want
If I want to chug an energy drink and black out for 3 hours in the middle of the day I'll fricking do it and if you ever threaten my supply I'll fricking kill you
Headaches are caused by caffeine withdrawal, kek.
Also reminder that caffeine keeps cortisol high all day long.
cluster headaches are caused by genetics and extreme stress, I can also assure you that my cortisol would be maxed all day long regardless of what I eat or drink
Shrooms cure cluster headaches take the psylocibin pill anon
The israelite fears the coffee drinker.
>cluster headaches
The real deal? In that case I'm sorry. What is it about the caffeine that prevents them, the intracranial pressure?
I told a doctor once that i chug caffeine and lie down and hes like does that help and i said yeah and he said keep doing it then
Caffeine improves bloodflow or relaxes the response that tightens bloodvessels i think but its a known nootropic stimulant thats synergistic with just about every analgesic so its good for basically any brain problem except seizures i think
>i chug caffeine and lie down and hes like does that help and i said yeah
that's textbook intracranial hypotension symptomatology and first line treatment, have you explored that possibility? it can be seen on mri
>another demoralization thread
NOS Chads don't pay attention
>Caffeine inhibits protein synthesis:
>https://pubmed.ncbi.nlm.nih.gov/28634643/
Have you ever heard the expression "the dose makes the poison"?
Let's figure out what human dose this cell culture study was working with.
>cells exposed to 5 mM caffeine for 6 h
Caffeine has a molar weight of 194.19g/mol.
A large cup of coffee has ~100mg of caffeine, or 0.1g.
0.095 g (1 mol / 194.19 g) = 0.000489 mol or 4.89 x 10-4 mol caffeine in one cup of coffee.
The present study bathed cells in 0.005 millimoles of caffeine for 6 hours.
In a lean adult of 70kg or so, 1 cup of coffee leads to a caffeine concentration of some 0.2mg/l.
0.2mg/l is 0.00001 moles per litre, or 0.01 mM/L.
5mM for 6 hours vs 0.01mM for a few hours from drinking 1 cup of coffee.
I appreciate the math but how many actual cups of coffee does that equate to in a 100kg human?
Literally more cups of coffee than it is possible to drink.
Like 700?
Not him, but FRICKING BRAINLETS
1 cup of coffee = concentration of 0.01
Concentration necessary to inhibit protein synthesis = 5
Cups of coffee necessary to reach a concentration of 5 = 500 (five hundred)
Yeah, if you drink five hundred cups of coffee within a day, you'll kill your gains. Also, you'll have a nice day due to glutamatergic excitotoxicity, so the gains aren't even relevant.
what the frick does this even mean?
the cells that had inhibited protein synthesis were bathed in an amount of caffeine that is 500x greater than your average cup of joe.
so basically a impossible amount of coffee or red bull or whatever the frick you're drinking
Okay i get it now. Thanks bros
cmon bro.
The study looked at cells exposed to 5M of caffeine for 6 hours.
The reality of drinking coffee would be 0.01mM exposed for a couple of hours.
The study does is 500x larger than what people normally consume.
Do you get it now?
Dont know but i drink coffee like 1-3 cup a day and along with green tea to suppress my hunger because im fasting. I drink it so i can flush my excess water to make my face & body more chiseled, because caffeine suppose to make your body excrete water like crazy. And it works bro.
Do i need to stop now? Do you have any substitution to suppress hunger homie?
Has anyone considered that sandBlack folk might be biologically adapted towards caffeine consumption? They were the first to consume it, after all.
I bet race plays a huge role in how your body handles this shit.
the basketball American is the only race I know of that doesn't like coffee
>drink coffee
>can live life no matter how many days into a fast I am
>don't drink coffee
>Zzzzzzzzzzz
ok, let's say that this is all true, how do I give 100% in the gym without caffeine?
by not being addicted to it? You shouldn't feel like you need stimulants
By sleeping more and getting more high QUALITY sleep, which you do by stop consuming caffeine, sleeping roughly at the same time each day, no screens before bed, and having a wind down routine before bed.
didn't read also having my mornin' cuppa
>decrease or increase in hunger
Yeah, try working month long nightshifts like me without caffeine.
It doesn't actually give you more energy, it just takes away the withdrawal symptoms when you drink it and stops you from sleeping at night.
It literally blocks the chemical that makes you feel tired/sleep/fatigued. I drink 2 cups a day and I sleep fine at night.
Like I said it prevents sleep. Your brain makes new adenosine receptors to adapt to caffeine use. When you stop caffeine, the adenosine floods the receptors making you beyond tired and causing headaches via vasodilation. Also blocking adenosine causes hair loss and interferes with sleep cycles and normal heart rhythm, causing arrythmias and fatigue. 85% of Americans are drug addicts.
>Americans
Black person the entire fricking world is addicted the bean israelite, and drives shit far more than you know.
Are you implying that caffeine causes hairloss? lol
>Like I said it prevents sleep
Lmao maybe if you drink it at 9PM you moron. I sleep just fine.
>believing some app
https://pubmed.ncbi.nlm.nih.gov/33378539/
>Consumer sleep-tracking devices are widely used and becoming more technologically advanced, creating strong interest from researchers and clinicians for their possible use as alternatives to standard actigraphy. We, therefore, tested the performance of many of the latest consumer sleep-tracking devices, alongside actigraphy, versus the gold-standard sleep assessment technique, polysomnography (PSG).
>Conclusions: Consumer sleep-tracking devices exhibited high performance in detecting sleep, and most performed equivalent to (or better than) actigraphy in detecting wake. Device sleep stage assessments were inconsistent. Findings indicate that many newer sleep-tracking devices demonstrate promising performance for tracking sleep and wake. Devices should be tested in different populations and settings to further examine their wider validity and utility.
they detect sleep, okay, but do they detect quality of sleep?
They detect sleep, and I can tell when I'm well-rested or not.
Your argument is literally "NO YOU'RE ACTUALLY NOT SLEEPING WELL, YOU'RE JUST IMAGINING THAT YOU'RE WELL-RESTED".
Don't be scares of a little caffeine bro. The dose makes the poison.
Yeah ok, I'll just do a little bit of heroin, I'll just do a little crack, I'll just take a few opioid pills, I'll just take a little penis in the ass
Either a substance is toxic or its not, what's so hard to understand?
You're just coping with your drug addiction and trying to stay somewhat normal socially
>Mild intake of alcohol INCREASES lifespan and DECREASES cardiovascular risk
>EiTheR sOmEtHiNg iS pOiSoN oR iT iSn'T
>Either a substance is toxic or its not, what's so hard to understand?
Lmaoing at your life pal. Literal kindergarten understanding of biology. Black and white binary thinking is symptomatic of autism.
Midwit take
The only difference between a poison and a medicine is in the dosage.
If you need an example go read about digoxin.
>Digoxin (better known as Digitalis), sold under the brand name Lanoxin among others, is a medication used to treat various heart conditions.[4] Most frequently it is used for atrial fibrillation, atrial flutter, and heart failure.[4] Digoxin is one of the oldest medications used in the field of cardiology. It works by increasing myocardial contractility, increasing stroke volume and blood pressure, reducing heart rate, and somewhat extending the time frame of the contraction
>The use of digoxin is limited because the drug has a narrow therapeutic index and requires close monitoring. Digoxin can cause many adverse events, is involved in multiple drug interactions, and can result in toxicity. Despite its limitations, however, digoxin has a place in therapy
EiTheR sOmEtHiNg iS pOiSoN oR iT iSn'T
But you can't tell if you're asleep?!?! Need an app for that?!?!
I drink preworkout at like 8pm because I'm too busy to workout anytime else. I can have coffee and go right to sleep. Sounds to me someone aint burning all their energy during the day
>the adenosine floods the receptors making you beyond tired
I like this tho. I drink coffee when I'm doing something important like lifting or video games and I get the added bonus of being sleepy later so I can daydream during meetings
Coffee pretty much kick started the industrial revolution.
Come on anon don’t make me worry needlessly while I’m drinking my morning coffee.
A thing is good for you if you live longer while doing it.
Which, in the case of caffeine (or at least coffee), you do. https://pubmed.ncbi.nlm.nih.gov/31055709/
I’m very familiar with the caffeine research and even gave it up for a few months and felt good. However, I just gotta have that early morning cuppa covfefe. Coffeemaker makes it at 6a, I run downstairs, make my cup, run back upstairs into my chilly bedroom and sip it under the covers curled up with my dog. It’s the highlight of my day.
I keep it to one cup a day. It’s still an addiction but I stay so disciplined in other areas that it feels ok to have this one.
>curled up with my dog.
You just KNOW
White women, BAKA
Hot take Black person
shhh, haven't had my second cup yet
Not to mention that when you ingest 100mg at 9 pm, you'll still have 25mg left in your system at 9 pm due to the 5-6 hour half life of caffeine, which causes worse sleep hygiene, which creates a dependence of caffeine. Not to mention that some people take 200mg worth of caffeine in their preworkout past noon. Yeah, good luck getting the benefits of a good nights sleep when you have to wake up at 6 the next day.
What about green tea. It has some caffeine although very low. I dont want to quit it. It provides large amounts of health benefits.
>be israelite "scientist"
>get a bunch of fatties with health problems
>do "tests"
>ask if they drink coffee
>they say yes
>"they have these problems because caffeine"
Don't forget that caffeine works against creatine and minimizes it's benefits, the only rebuttal a gymbro has to this is "b-b-but it was just one study!!!" Yea and it proves that if you take creatine you shouldn't take caffeine, lol
Min maxers deserve the rope. Perfect is the enemy of good.
This logic implies anyone that does not take creatine but drinks coffee would negate any benefits from any natural creatine consumed from food or created by their body.
The study specifically shows that taking creatine + caffeine has the same effects as not taking creatine, I forgot what it's called but I'm sure you can find it if you look
Ah, i see. I'll goggle myself it when if i get bored.
Just drink it in the morning moron
Can somebody explain to me why coffee gives me anxiety but other sources of caffeine dont?
Coffee makes me like jittery as frick and anxious. But if I drink preworkout, energy drinks, tea, whatever the frick with the same amount of caffeine I dont have this
Same for me, my guess is the added stuff like inositol and niacin.
Imagine listening to 'them' I fricking love tasking PWO. Been taking it a few times a week for over a decade
My mom drank coffee heavily during birth.
I’m 6’7” and 230 lbs and better hung than tommy lee angle frauding.
My oma is 95 in great health and says it’s because of her always drinking strong coffee, and I’ll take what she says over some credentialed homosexual diversity hire in an oversized white coat who thinks his rote memorization of someone else’s knowledge somehow entitle xim or xer to a position of authority.
Not even going to touch on the replication crisis in “science”.
Frick you OP, go frick your self with a rake
Should I switch to green tea?
frick off moron. science is gay and so are you. you should be stuffed in a locker somewhere
Now find the articles linking coffe to a decrease in MS
It's almost as if coffee is a very mild drink like water with flavouring and is not actually linked to anything except mild stimulation in people who aren't used to drinking it and all this science is a load of nonsense based off of spurious correlations designed just to get millions of dollars of research funding.
http://www.tylervigen.com/spurious-correlations
>MS
Microsoft? Multiple Sclerosis? Morgan Stanley? Master System? Mississippi?
Millisecond?
you forgot : coffee reduces blood flow to the brain by 30 to 40 pct and other vasoconstriction
Shut up loser
t. caffeine chad lifting twice as much as you and hogging all the mires in the gym
Also it causes birth defects and babies to be born underweight and with diminished mental abilities. Actually it prevents a lot of women from becoming pregnant in the first place.
>Check first study
>Subject are cells
Come back when they do a full study by comparing two groups of people, one with cafeine and the other on placebo.
cope pathetic addict
Post heart rate ( you won't)
not gonna read all that shit
next time post dosages if you want to have a discussion
dont care still drinking coffee
dont care about those non-sides
>premature birth
lmao
Ill take my increased focus and the free test boost, u take ur decreased risk of seizures lmaooo
I knew this starbucks normie drug was toxic. I can't chew on coca leaves throughout the day for energy but this shit is freely available without regulation. America has lost its way.