So longevity?

So longevity /b/ros, what's the latest scoop on the frontier? Will life extension be successful within the next 30 years?

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  1. 1 month ago
    Anonymous

    Dude with shoes updated his crg rentry. Results look good. Going to do my second stack of it in maybe 6 months. Want to do a bunch of fasting when it's not cold out

    • 1 month ago
      Anonymous

      link please?

    • 1 month ago
      Anonymous

      Who is dude with shoes? Saw his name mentioned in a couple of threads... is there a comunity that focuses on longevity?

      • 1 month ago
        Anonymous

        https://rentry.org/CR_General

    • 1 month ago
      Anonymous

      how much did the stack cost all in? From the quantities he's using it looks quite expensive.

    • 1 month ago
      Anonymous

      Any noticable effects?

  2. 1 month ago
    Anonymous

    Can somebody poke Elon Musk/Jeff Bezos on Twitter to put some money towards immortality research?

    • 1 month ago
      Anonymous

      leave the funding to me

  3. 1 month ago
    Anonymous

    tell richard de greymes here to stop shilling for the ivans and the epstein cabal, stop creeping on women, and publish something

    or start studying yourself and quit the hero worship.

  4. 1 month ago
    Anonymous

    yeah rmr 1 is a complete success and we are going to live past 100+ years at a minimum if we take TERT, rapamycin, and senolytics. Probably even longer since we're gonna almost certainly live past LEV with this stack

    • 1 month ago
      Anonymous

      Are those widely available yet?

      • 1 month ago
        Anonymous

        senolytics and rapamaycin are yeah

        • 1 month ago
          Anonymous

          what kind of dosages are we talking about? good vendors?

          • 1 month ago
            Anonymous

            You can get it shipped from India if you search. I wouldn’t put myself on Rapamycin, although I know it works. It turns down immune system. I’d turn into a bowl of viruses.

            • 1 month ago
              Anonymous

              You can use rapamycin at subclinical doses, below what is used for transplant recipients, to reduce the immune system dampening. You can also blast & cruise it for an acute strong dose.

        • 1 month ago
          Anonymous

          >rapamaycin
          ever wondered how people manage to know that you're israeli?

          • 1 month ago
            Anonymous

            but im not israeli you fricking moron
            does /misc/ not like rapamycin for some reason?

            • 1 month ago
              Anonymous

              for it is being pushed solely by israelites who avoid mentioning its nefarious side-effects and that it only works in rats (which they probably are)

  5. 1 month ago
    Anonymous

    Lucius debeers says he's cold.

    • 1 month ago
      Anonymous

      18 degrees celsius to be exact

    • 1 month ago
      Anonymous

      gotem!

  6. 1 month ago
    Anonymous

    troony thread

    • 1 month ago
      Anonymous

      transhuman thread, big difference
      have fun dying painfully monkey

      • 1 month ago
        Anonymous

        What's funny is you think you won't die. That mid life crisis is gonna hit you hard

        • 1 month ago
          Anonymous

          https://www.levf.org/projects/robust-mouse-rejuvenation-study-1/study-updates/may-7th-2024
          look at the fricking graph

        • 4 weeks ago
          Anonymous

          >What's funny is you think you won't die. That mid life crisis is gonna hit you hard
          THIS.
          I'm all for research into aging but the reality for hundreds of years into the foreseeable future is that you ARE going to die and only live on 50% through your children.

          Can somebody poke Elon Musk/Jeff Bezos on Twitter to put some money towards immortality research?

          >Can somebody poke Elon Musk/Jeff Bezos on Twitter to put some money towards immortality research?
          They know it's bullshit. You're a gullible idiot. That's also why you have no money or children and suffer from severe autism spectrum disorder.
          You need to be the opposite of immortal.
          You can't die fast enough.

          • 4 weeks ago
            Anonymous

            >They know it's bullshit. You're a gullible idiot. That's also why you have no money or children and suffer from severe autism spectrum disorder.
            >You need to be the opposite of immortal.
            >You can't die fast enough.
            kek facts

    • 1 month ago
      Anonymous

      spam

      What's funny is you think you won't die. That mid life crisis is gonna hit you hard

      nobody says this, longevity involves being healthier for longer so lifespan is naturally extended, good for everyone
      you are just some weird guy obsessed with being negative about this topic in particular

      • 1 month ago
        Anonymous

        Healthy living is already a thing but only rich people with time to train, eat healthy and able to relax with fun pastimes can do these. Everyone else works, catches some food, some sleep and worries

  7. 1 month ago
    Anonymous

    not yet. the day he shaves his beard will be the day a cure to longevity is ready. everyone will say "wow he looks so much younger without his beard, that longevity treatment must work wonders" and throw money at him

  8. 1 month ago
    Anonymous

    Has anyone ever bred rats or some simpler organism for longevity? The idea is you freeze some rat sperm and eggs and see how long the rats live, then you use the sperm and eggs of the ones that lives the longest to breed a new generation. Seems very simple.
    Another solution, cheaper to perform, would be to track a rat population for typical signs of aging, like memory problems and pick the ones that seemed less aged (for their age) and use these for breeding.

    • 1 month ago
      Anonymous

      What would be the purpose of that study?
      What is wrong with you eugenics morons??? Why do you always think in impractical terms of generations of top down control and selective breeding instead of TREATMENTS

      • 1 month ago
        Anonymous

        >What would be the purpose of that study?
        To determine if its possible to lengthen the lifespan of an organism through selective breeding and if yes, to how much

      • 1 month ago
        Anonymous

        >What would be the purpose of that study?
        To determine if its possible to lengthen the lifespan of an organism through selective breeding and if yes, to how much

        Also, there isnt any contradiction between researching longevity via eugenics or thorough treatments. With eugenics you get examples of improved organisms and you can then study the differences in their biology, and use that to design treatments. It helps a lot to even know that such things would be possible.
        Like, it would help with funding in general if someone bred a rat that lived 40 years

    • 4 weeks ago
      Anonymous

      >Has anyone ever bred rats or some simpler organism for longevity? The idea is you freeze some rat sperm and eggs and see how long the rats live, then you use the sperm and eggs of the ones that lives the longest to breed a new generation. Seems very simple.
      >Another solution, cheaper to perform, would be to track a rat population for typical signs of aging, like memory problems and pick the ones that seemed less aged (for their age) and use these for breeding.
      I do remember that being done in a thirty? year old European experiment. Can't find the article right now. It does work. The average age does measurably increase each generation. Just very slowly. Evolution itself is proof that it works.

      What would be the purpose of that study?
      What is wrong with you eugenics morons??? Why do you always think in impractical terms of generations of top down control and selective breeding instead of TREATMENTS

      >What would be the purpose of that study?
      >What is wrong with you eugenics morons??? Why do you always think in impractical terms of generations of top down control and selective breeding instead of TREATMENTS
      ? There is no possible way of making an ordinary lab rat live for 30 years. You can't defeat genetics. It always wins. It is always the final frontier.
      Nature on the other hand has evolved other rodents to live for over 30 years.
      Nature has evolved a 500+ year lifespan for Greenland sharks.
      Like a bicycle, the only way you could make a human live indefinitely without genetic modification is by replacing identical parts. So you grow a clone of yourself to use for replacement parts.
      That however doesn't work when it comes to brain rejuvenation. You're still fricked there.

  9. 1 month ago
    Anonymous

    >Will life extension be successful within the next 30 years?
    >successful
    We got an octogenarian running against a near-octogenarian. Yesterday, the octogenarian President was surrounded by 100 year old D-Day vets. You tell me.

    I'm with Ray Kurzweil...longevity escape velocity by 2030. No one alive at that date in a Western country dies of a thing called "old age" after that.

    • 1 month ago
      Anonymous

      Yeah the tech is here already and only getting better

    • 1 month ago
      Anonymous

      Soon you'll be lucky if you can die

      • 1 month ago
        Anonymous

        You can't live for long even with theoretically working limitless longevity tech. Our brains probably aren't made to last that long and the memory bandwidth is limited even if it's large. What are you gonna start randomly forgetting vital shit after you hit the 300 year mark? Delusional.
        I think as a society the best semi-realistic thing to hope for is not longevity but youth.
        For us to live normal human lifespans (maybe slightly longer due to better tech, like up to 150 years old) but stay basically 20-year-olds until something suddenly fails. That would be the best possible (even if a pretty unrealistic) outcome.

        • 1 month ago
          Anonymous

          >What are you gonna start randomly forgetting vital shit after you hit the 300 year mark?
          homie, you already forgot 90% of your childhood. Stfu.

          • 1 month ago
            Anonymous

            I remember a lot of crucial moments up to being 2 years old. Yes I probably don't remember every day-to-day (remember a lot of random mundane flashes though), but I remember enough for it to be a solid sense of continunity and identity. Now imagine if that starts going away. You have dementia at this point.

            • 1 month ago
              Anonymous

              Yeah, it must be really vital, that memory of how you pooped your pants once when you were 4. I don't know how you'd be able to live without it.
              Maybe you should die right now, to make sure you don't forget it before you die.

          • 1 month ago
            Anonymous

            I'm 30 and still remember my first memory, what the frick are you blabbling about?

            • 1 month ago
              Anonymous

              Describe every meal you've had in your life starting from the beginning

              • 1 month ago
                Anonymous

                Your mom's pussy
                Your mom's pussy
                Your mom's pussy
                Your mom's pussy
                Your mom's pussy....

              • 1 month ago
                Anonymous

                I hope you give some good head.

              • 1 month ago
                Anonymous

                A succulent chinese meal
                Steamed hams
                A succulent chinese meal
                Pretzel
                Foreskin
                A succulent chinese meal

              • 4 weeks ago
                Anonymous

                >A succulent chinese meal
                Lol, You're quoting Charles Dozsa.
                Nice.
                Talking about longevity, the guy is still alive too.

                Crazy, he was an old fricker many decades ago.

        • 4 weeks ago
          Anonymous

          >For us to live normal human lifespans (maybe slightly longer due to better tech, like up to 150 years old) but stay basically 20-year-olds until something suddenly fails.
          if you achieve that you've already achieved biological immortality. Nobody is going to be a walking mummy

    • 4 weeks ago
      Anonymous

      >We got an octogenarian running against a near-octogenarian. Yesterday, the octogenarian President was surrounded by 100 year old D-Day vets. You tell me.
      Mentally and physically dead people that look like senile grim reapers are your argument for modern "life extension"?
      The oldest person to ever live died in 1997.
      The life expectancy of Americans today is 77 years.

      >I'm with Ray Kurzweil...longevity escape velocity by 2030.
      And when 2030 passes you will make up a new prediction for 2040...
      Frick off with that shit.

      • 4 weeks ago
        Anonymous

        The human body is only but so complex. We've already mapped out most of the pathogenic mutations for common genetic diseases. While 2030 and 2040 and the like always seems to be a moving target for this poorly defined "escape velocity" BS, do you really think we'll still have cancers and Alzheimers by 2100?

        • 4 weeks ago
          Anonymous

          >The human body is only but so complex
          And it's still beyond our complete understanding because it is far too complicated.

          >We've already mapped out most of the pathogenic mutations for common genetic diseases.
          No we haven't. We've got no idea what the frick is going on 90% of the time. It's always just noticing vague patterns and correlations. Useful information but nothing close to a complete understanding.

          >While 2030 and 2040 and the like always seems to be a moving target for this poorly defined "escape velocity" BS, do you really think we'll still have cancers and Alzheimers by 2100?

          Holy shit are the "cure cancer" people stupid.
          There are hundreds of different cancer types that all need completely different treatments or possible gene modifications to remove them as ailments.
          Personally the most promising treatment now involves immune system tweaking but even that is fought with dangers.
          An immune system that removes your Brain tumor can also continue on to attack your own non-cancerous CNS.
          So you need a biological switch to turn it off and on. Something that doesn't exist yet.
          Humans simply haven't evolved to live beyond 40.
          Alzheimer's/Dementia is also exceedingly complicated and poorly understood. Almost everyone in their 70's has significant cognitive decline compared to their 30's regardless of their disease status. Brain immortality without a doubt is the hardest of all. It is 1000% more complicated than other parts of the body. It is insane to even suggest that's achievable in 200 years.

          • 4 weeks ago
            Anonymous

            >There are hundreds of different cancer types that all need completely different treatments or possible gene modifications to remove them as ailments.

            Just look at the survival statistics for melanoma and non-small cell adenocarcinoma, for example. Used to be pretty damn fatal 20-30 years ago, now most patients are surviving with immunotherapy. This trend will obviously continue towards better and better survival for more and more cancers over time.

            • 4 weeks ago
              Anonymous

              >Just look at the survival statistics for melanoma

              "In the last decade, the 5-year overall survival rate for advanced melanoma has increased from <10% to >50%."
              https://melanoma.org.au/about-melanoma/melanoma-facts/

              Yes, that's a very significant improvement but it isn't anything close to immortality.
              My titanium bike is still going to break. It will just take longer to break than an aluminium bike.

              Most of the improvement with skin cancer is just people being more proactive with getting their skin checked. Also less patients are Caucasian. The most at risk group in the world for skin cancers.

              • 4 weeks ago
                Anonymous

                But don't forget, there is still *constant* technical progress unless something drastically disrupts civilization. Now you can get carbon fiber bikes, and next they'll probably have M5/PIPD fiber bikes, etc...

            • 4 weeks ago
              Anonymous

              skin cancer is caused by sunscreens

              • 4 weeks ago
                Dr. No

                Make your own titanium oxide and mix it with any plant oil you can extract that works for you.

              • 4 weeks ago
                Anonymous

                >plant oil
                good one

              • 4 weeks ago
                Anonymous

                personally i slather myself with raw petroleum, straight from nature

              • 4 weeks ago
                Dr. No

                I have no idea what you would prefer. Titanium oxide is the best UV blocker there is, and it is VERY non-poisonous.

  10. 1 month ago
    Anonymous

    >life extension
    Oh, I thought this was about penis extension. I'm out.

  11. 1 month ago
    Anonymous

    Just die with some dignity like every human being before you.

    • 1 month ago
      Anonymous

      >Just die with some dignity
      Sure, but theres nothing undignified about dying with dignity later

      • 4 weeks ago
        Anonymous

        your fear of death is childish and pathetic

    • 1 month ago
      Anonymous

      >like every human being
      are you dumb? it's only ever been a lucky few who die that way

    • 1 month ago
      Anonymous

      I watched my great-grandparents die. There's nothing dignified about being a mass of health issues riddled with dementia, shitting and drooling on yourself while the nurses steal your israeliteellery.
      If healthspan isn't improved, I'm going to take myself out once I start declining when I still have the ability to do so.
      Ideal situation would be good health until something critical fails and I die quickly. Frick the slow fade

  12. 1 month ago
    Anonymous

    [...]

    you cannot stop biologic immortality (elimination of aging) and absolute immortality is not even promised to be ever on the table
    Either way, why are you gay?

  13. 1 month ago
    Anonymous

    I saw a paper on epigenetic reprogramming. It said 2-4 days of treatment would do a full programb, and the results last 6-7 days. So there you go. You can do apigenin or whatever treatment max 4 days before it *stops working*. The results last for about a week, where you could try to build new tissue? Then start up again if you need. Which kind of mimics a lot of other experiments with senolytic therapy.

    I don’t know if it will actually cause you to live longer, it might not.

  14. 1 month ago
    Anonymous

    What do people here think about Bryan Johnson? Did he actually stop/reverse aging like he claims or is he a larp?

    • 1 month ago
      Anonymous

      I'm on his blueprint stack right now
      His speed of aging is 0.62 so he has slowed his speed of aging
      His organ function has been rejuvenated across the board (some of them to the level of a teenager) so he has legitimately made himself biologically younger
      The gene therapy he's taken extended lifespan in mice by 35-40 percent
      Same with the full body stemcell injections
      Unless something happens to him he is going to live past LEV and rejuvenate himself further
      Dave Pascoe is a more interesting biohacker though. He has an extrinsic age of 37 but is 61. He also takes telomerase extending drugs and looks physically to be in his late thirties or early forties.

      • 1 month ago
        Anonymous

        >I'm on his blueprint stack right now
        How's it working out for you? Is it something you would recommend?
        >Dave Pascoe is a more interesting biohacker though
        I've looked into him a bit. Isn't it a big red flag that he doesn't show himself anywhere in the media, though? His claims are very bold.

        • 1 month ago
          Anonymous

          why would he? the added stress of constant media attention is probably pretty damaging to his goals.

        • 1 month ago
          Anonymous

          >How's it working out for you?
          Miraculously. People at work are constantly commenting on my looks now saying I look younger than I was hired so it's definitely deaging me. I'm also more energized and for some reason I barely get sore after going nuts at the gym now.
          >Is it something you would recommend?
          Yes.

          Pascoe has videos of himself and his tests online. Him not being in the media might just be because he's just some dude and not a centimillionaire influencer like BJ.

  15. 1 month ago
    Anonymous

    https://www.scientificamerican.com/article/immortal-line-of-cloned-mice/
    MARCH 8, 2013
    2 MIN READ

    Immortal Line of Cloned Mice Created

    Mice can be cloned via somatic cell nuclear transfer from other mice indefinitely, a new technique suggests. The technique could be used for large-scale production of superior-quality animals for farming or conservation purposes

    In their study, Wakayama and colleagues grew the cloned cells in a solution containing trichostatin, a compound that interferes with enzymes that make changes to DNA. Using this technique, the cloning process was five times more successful.

    The team successfully cloned the mice 25 consecutive times. In other words, they cloned one mouse, then cloned those clones, and so on. A total of 581 healthy mice were made, all of which were fertile and lived a normal life span of about two years. The efficiency of making the cloned cells neither worsened nor improved over the generations.

    https://www.independent.co.uk/news/science/gene-long-life-tested-mice-b2398496.html
    Scientists find gene that grants long life – and successfully test it on another species
    Genetically modified mice found to have less inflammation and healthier gut

    Vishwam Sankaran
    Thursday 24 August 2023 08:13 BST

    Scientists successfully introduced into mice a gene responsible for making high molecular weight hyaluronic acid (HMW-HA) – a molecule responsible for naked mole rats’ unusual resistance to cancer.

    Previous studies have shown that compared to mice and humans, the mole rats have about 10 times more HMW-HA in their bodies, and when the molecule’s gene was removed from the rats, their cells were more likely to form tumours.

    In the new research, scientists genetically modified mice to produce the naked mole rat version of the hyaluronan synthase 2 gene – responsible for making a protein that produces HMW-HA.

    • 4 weeks ago
      Anonymous

      >Immortal Line of Cloned Mice Created
      Living for 2 years isn't immortal.
      Cloning like sexual reproduction isn't immortality.

      >Scientists successfully introduced into mice a gene responsible for making high molecular weight hyaluronic acid (HMW-HA) – a molecule responsible for naked mole rats’ unusual resistance to cancer.
      Mole rats are more susceptible to cancer than humans and only live for 30 years at most...

      https://www.nih.gov/news-events/nih-research-matters/gene-rejuvenates-mouse-embryonic-stem-cell-immortality

      March 29, 2010

      Gene Rejuvenates Mouse Embryonic Stem Cell Immortality
      Confocal microscope image of red spots on green tips of chromosomes
      Researchers have discovered a key to mouse embryonic stem (ES) cell rejuvenation in a gene called Zscan4. If a similar mechanism also operates in human cells, the finding could have major implications for aging research, stem cell biology, regenerative medicine and cancer biology.

      ES cells are unique not only because of their ability to develop into nearly any type of cell in the body. They are also what scientists call immortal—they can divide indefinitely in the laboratory to produce new generations of fully functional "daughter" ES cells. Other cells can only produce a certain number of generations of daughter cells before they no longer function properly. This is partially because the telomere, the protective end of the chromosome, shortens each time a cell divides. When a telomere becomes too short, the cell dies, turns itself off or produces abnormal cells.

      As reported in the March 24, 2010, online edition of Nature, only about 5% of ES cells have Zscan4 activated at any given time. However, nearly all ES cells undergo a period of Zscan4 activation. When the researchers interfered with Zscan4 expression, cell population growth slowed and eventually reached a crisis, with massive cell death.

      The researchers examined telomeres and found that Zscan4 activation led to telomere lengthening. However, telomerase—a protein known to elongate telomeres in other situations—didn't seem to be involved. Rather, Zscan4 activation turned on genes involved with recombination—the process by which DNA strands are broken and joined to other strands. ZSCAN4 protein, along with these recombination proteins, could all be found on telomeres during this telomere "rejuvenation" phase.

      >ES cells are unique not only because of their ability to develop into nearly any type of cell in the body. They are also what scientists call immortal
      Nothing impressive about this what so ever. Cancer cells are also technically immortal...
      You need to actually demonstrate some achievement at indefinitely extending the life of a mammal.

  16. 1 month ago
    Anonymous

    https://www.nih.gov/news-events/nih-research-matters/gene-rejuvenates-mouse-embryonic-stem-cell-immortality

    March 29, 2010

    Gene Rejuvenates Mouse Embryonic Stem Cell Immortality
    Confocal microscope image of red spots on green tips of chromosomes
    Researchers have discovered a key to mouse embryonic stem (ES) cell rejuvenation in a gene called Zscan4. If a similar mechanism also operates in human cells, the finding could have major implications for aging research, stem cell biology, regenerative medicine and cancer biology.

    ES cells are unique not only because of their ability to develop into nearly any type of cell in the body. They are also what scientists call immortal—they can divide indefinitely in the laboratory to produce new generations of fully functional "daughter" ES cells. Other cells can only produce a certain number of generations of daughter cells before they no longer function properly. This is partially because the telomere, the protective end of the chromosome, shortens each time a cell divides. When a telomere becomes too short, the cell dies, turns itself off or produces abnormal cells.

    As reported in the March 24, 2010, online edition of Nature, only about 5% of ES cells have Zscan4 activated at any given time. However, nearly all ES cells undergo a period of Zscan4 activation. When the researchers interfered with Zscan4 expression, cell population growth slowed and eventually reached a crisis, with massive cell death.

    The researchers examined telomeres and found that Zscan4 activation led to telomere lengthening. However, telomerase—a protein known to elongate telomeres in other situations—didn't seem to be involved. Rather, Zscan4 activation turned on genes involved with recombination—the process by which DNA strands are broken and joined to other strands. ZSCAN4 protein, along with these recombination proteins, could all be found on telomeres during this telomere "rejuvenation" phase.

  17. 1 month ago
    Anonymous

    Longevity research is pseudoscience that targets atheists

    • 1 month ago
      Anonymous

      I bet you catholic pederast cannot even read microbiology.

  18. 1 month ago
    Anonymous

    >Will life extension be successful within the next 30 years?

    No.

  19. 1 month ago
    Anonymous

    >YOU VILL BECOME ELDERLY AND YOU VILL LIKE IT
    He was our only chance, MeToo doomed life extension. There is no hope even if the most knowledgeable biotechnicians start taking it seriously today. There are like a dozen aging-related phenomena and barely one of them has been solved so far

    • 1 month ago
      Anonymous

      Do you ever think before running your mouth?

      • 1 month ago
        Anonymous

        Just two more weeks then the government will allow gene editing

        • 1 month ago
          Anonymous

          go to mexico, columbia, or prospero
          or just do it illegally

  20. 1 month ago
    Anonymous

    wait who tf is this

    • 1 month ago
      Anonymous

      Get farted on kyads

      • 1 month ago
        Anonymous

        Basically they got farted on for 600 years and it was very painful and confused from reality, in such a way that any hell we could possibly do would be miniature. Sweet sweet revenge. Several little poo balls on a plate, served with diseases inside - cracked up perfect. Under the sweetest Sun, one hundred times the size grew up quickly against a prepared sun. Pissed off about life? Try looking at these people, really getting into their deranged minds.

        • 1 month ago
          Anonymous

          Fart on ME NOW

          Unless ya cant

  21. 1 month ago
    Anonymous

    You're all gonna live a short, mostly meaningless existence, then deteriorate, waste up to a third of your already-short life on being old and in poor health, and finally die in a hospital somewhere (which is going to be very scary), probably in a pretty painful way. Then it's gonna be dark for eons and eons, the darkness quickly erasing any meaning or imprint you might've left on this Earth otherwise. Have fun.

    • 1 month ago
      Anonymous

      what's your life like bro? I'm getting a israeli feel from you

      • 1 month ago
        Anonymous

        Not good (also not israeli).
        Don't see what it has to do with the matter at hand, however. Cope isn't going to help with hardship in the long run.

    • 4 weeks ago
      Anonymous

      >You're all gonna live a short, mostly meaningless existence, then deteriorate, waste up to a third of your already-short life on being old and in poor health, and finally die in a hospital somewhere (which is going to be very scary), probably in a pretty painful way.
      Most people aren't chronically depressed autistic friendless genetic rejects like you anon...

      >Then it's gonna be dark for eons and eons, the darkness quickly erasing any meaning or imprint you might've left on this Earth otherwise. Have fun.
      Lol, Nobody knows what happens after death. You're just as delusional as an Abrahamic at this point.

      • 4 weeks ago
        Anonymous

        >Lol, Nobody knows what happens after death. You're just as delusional as an Abrahamic at this point.
        >t. billy bob who just left evangelicalism and joined some neopagan/occult larp
        religion is religion and you won't find allies on IST of all boards simply because you chose to rebrand from one belief in paranormal to another

        • 4 weeks ago
          Anonymous

          Where are the Pagans anon?
          I simply said Abrahamic because 99.999% of all religious people on IST are Abrahamics...

          • 4 weeks ago
            Anonymous

            >99.999% of all religious people on IST are Abrahamics...
            99.999% of all religious people on IST are culture war LARPers. Five years ago they were LARPing as Abrahamics, these days they're more inclined to LARP as pagans and fight with the remaining Abrahamic LARPers and call them Christcucks. In reality, they are all bored atheists who jerk off to trap porn.

            • 4 weeks ago
              Anonymous

              >99.999% of all religious people on IST are culture war LARPers
              You aren't wrong.

  22. 1 month ago
    Anonymous

    https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2024.1399676/full
    Hope you bros didn't vaxx

  23. 1 month ago
    Anonymous

    Why would anyone want to live longer?

    • 1 month ago
      Anonymous

      Why not? Therr aren't enough lifetimes to study everything the world has to offer. Also, no mayter how much I age, 18 year old girls are still 18.

      • 1 month ago
        Anonymous

        Life has (less than) nothing to offer.

  24. 1 month ago
    Anonymous

    She's 75, she could be onto something.

    • 1 month ago
      Anonymous

      Same person with no filters...

      • 4 weeks ago
        Anonymous

        that's pretty good for 75. A lot of women look like this at 50

  25. 1 month ago
    Anonymous

    why doesn't he fast, ISTncels?

    • 1 month ago
      Anonymous

      Probably because it interrupts with all the shit he's taking. No one in history popped as many pills as he does on a daily basis.

  26. 1 month ago
    Anonymous

    So, any of the methods ITT scientifically proven to work? Or is it just trustmebro/e-celebs/snake oil? How much do such treatments cost?

    • 1 month ago
      Anonymous

      oh my fricking god man, just look at the RMR study, I posted it at the top of the thread
      why do you ask dumbass shit like this?
      READ THE FRICKING THREAD

    • 4 weeks ago
      Anonymous

      >you need to extend my life for me
      lol. 100% youre vaxxed

  27. 4 weeks ago
    Anonymous

    Oxygen restriction is the real thing

    • 4 weeks ago
      Anonymous

      nah, i have 30% lung capacity and i'm aging like milk

  28. 4 weeks ago
    Anonymous

    Looks like this thread (which is not Scientific nor Mathematical and therefore Off-Topic and Extremely Low Quality) is not going to be saved from removal. In other words, I'm Not Bumping This Thread.

  29. 4 weeks ago
    Anonymous

    kek, they can't even cure baldness or stop hair graying, and they sit around on Twitter pounding their meat over far more ambitious ideas.

    • 4 weeks ago
      Anonymous

      you haven't seen those red light helmet things?

      I started losing hair a few years back and started Rogaine, it was kinda meh worked ok. Threw on the red light helmet, my hair is almost back to 18-year old levels.

      • 4 weeks ago
        Anonymous

        How do I know you're not just snickering at the thought of me posting to IST while wearing a laser helmet and elbow pads?

        • 4 weeks ago
          Anonymous

          https://www.liebertpub.com/doi/abs/10.1089/fpsam.2021.0151

          >Conclusions: All the articles selected and analyzed reported a positive effect of LLLT for MPHL and/or FPHL treatment without side effects.

          • 4 weeks ago
            Anonymous

            The trouble is that "positive effect" in the medical literature can be very underwhelming. Look at the before/after pics in the finasteride studies, for instance. Any uptick in hair density is considered a positive effect, yet...the dudes are still bald. The same thing happens in the microneedling studies.

            • 4 weeks ago
              Anonymous

              the red light helmets don't work for everyone, but the good results are pretty dramatic, like from "bald" to "decent hair"

              • 4 weeks ago
                Anonymous

                >the red light helmets don't work for everyone, but the good results are pretty dramatic, like from "bald" to "decent hair"
                They don't work for anyone. You have been completely conned you stupid moron.

                you haven't seen those red light helmet things?

                I started losing hair a few years back and started Rogaine, it was kinda meh worked ok. Threw on the red light helmet, my hair is almost back to 18-year old levels.

                >you haven't seen those red light helmet things?
                The idiot helmets for idiots. Well done for identifying yourself.

                The trouble is that "positive effect" in the medical literature can be very underwhelming. Look at the before/after pics in the finasteride studies, for instance. Any uptick in hair density is considered a positive effect, yet...the dudes are still bald. The same thing happens in the microneedling studies.

                >The trouble is that "positive effect" in the medical literature can be very underwhelming. Look at the before/after pics in the finasteride studies, for instance. Any uptick in hair density is considered a positive effect, yet...the dudes are still bald. The same thing happens in the microneedling studies.
                Holy shit you fricking idiot. Nobody here ever understands anything ever.
                Finasteride DOESN'T REGROW your head hair.
                It slows down or stops further hair loss.
                Finasteride also has very negative side effects.

              • 4 weeks ago
                Anonymous

                >Finasteride DOESN'T REGROW your head hair.
                Learn to fricking read, you oblivious midwit. All you're doing is amplifying the poster's point about how meaningless the phrase "positive effect" is in the medical lit.
                Also, you finasteride troons always claim "muh pause button, not rewind button," but finasteride (and dutasteride) are indeed peddled as regrowth agents in the medical lit.

              • 4 weeks ago
                That doomsday clock

                Seriously baldness...

                Try not knowing things about the people you are talking to and rub it in their faces

              • 4 weeks ago
                Anonymous

                I read what you wrote. You thought and still think that Finasteride regrows hair...
                It doesn't.
                You're a moron.
                You will forever be a moron.
                You will always have a small brain.

                But don't forget, there is still *constant* technical progress unless something drastically disrupts civilization. Now you can get carbon fiber bikes, and next they'll probably have M5/PIPD fiber bikes, etc...

                >But don't forget, there is still *constant* technical progress unless something drastically disrupts civilization
                Exactly, that's an important point.
                Whites will be gone and all you will have left to continue scientific progress is the Middle - Easterners and East Asians.
                I imagine that will grind down progress to a halt.

              • 4 weeks ago
                Anonymous

                >Whites will be gone and all you will have left to continue scientific progress is the Middle - Easterners and East Asians.

                And how exactly do you see this "replacement" occurring, great Nostradamus of IST?

              • 4 weeks ago
                Anonymous

                >And how exactly do you see this "replacement" occurring, great Nostradamus of IST?
                London and America are a majority non-white...

              • 4 weeks ago
                Anonymous

                >America
                >majority non-white
                i get that SJW academics have been extrapolating transient population trends to infinity and pretending hispanics are a "black and brown ethnicity" and not just a language group for a while now, but even in their ideal fantasy models America remains majority white until like the 2050s-2060s

              • 4 weeks ago
                Anonymous

                >and pretending hispanics are a "black and brown ethnicity"
                Pretending?
                Your Mexicans / Cubans etc are literally an unholy mix of Spanish whites, Native Americans and Africans.

                >but even in their ideal fantasy models America remains majority white until like the 2050s-2060s
                Literally now, today. America is a Majority non-white you complete and utter moron.
                Literally now, today. London is a Majority non-white, you complete and utter moron.
                Wake the frick up.

                I have no idea what you would prefer. Titanium oxide is the best UV blocker there is, and it is VERY non-poisonous.

                >Titanium oxide is the best UV blocker there is, and it is VERY non-poisonous.
                Yep, it's inert that it's even used as a food colorant.

              • 4 weeks ago
                Anonymous

                There's nothing wrong with Hispanics. Stop being a racist butthole.

              • 4 weeks ago
                Anonymous

                >There's nothing wrong with Hispanics. Stop being a racist butthole.
                Lol, see. Now you're admitting that Hispanics aren't white.
                Your covers off.
                Mexicans don't give a flying frick about your life anon. Doesn't matter how many times you suck their dicks.
                Also guess what? Everyone's racist.
                Welcome back to reality.

  30. 4 weeks ago
    Anonymous

    Not at all. First we need to solve the israelite problem, otherwise they will keep creating all types of diseases for profit.

  31. 4 weeks ago
    Anonymous

    VVVGGHHH

  32. 4 weeks ago
    Anonymous

    are there some actual advances in this field? Like reducing telomere degradation?

  33. 4 weeks ago
    Anonymous

    dont know but i take 12g vitamin c per day.
    also dont forget paul linus started taking vitamin c when he was allready old.
    imagine when you start young with megadose vitamin c.

    • 4 weeks ago
      Anonymous

      Vitamin C makes no difference when mega dosed because the surplus is simply excreted and gives you diarrhea.
      It's not going to drastically increase your life.

  34. 4 weeks ago
    Dr. No

    >Will life extension be successful within the next 30 years?
    Actually, we have achieved it. Immortals figure out a way to make women SHUT THE FRICK UP.

  35. 4 weeks ago
    Anonymous

    >No baldness cure yet
    >Thinks we can cure death

    Sure

    • 4 weeks ago
      Anonymous

      >>No baldness cure yet
      microneedling, finasteride, and minoxidil
      idiot

      • 4 weeks ago
        Anonymous

        >finasteride
        enjoy ur eunuchs transition or go read

        you haven't seen those red light helmet things?

        I started losing hair a few years back and started Rogaine, it was kinda meh worked ok. Threw on the red light helmet, my hair is almost back to 18-year old levels.

        https://www.liebertpub.com/doi/abs/10.1089/fpsam.2021.0151

        >Conclusions: All the articles selected and analyzed reported a positive effect of LLLT for MPHL and/or FPHL treatment without side effects.

        • 4 weeks ago
          Anonymous

          >enjoy ur eunuchs transition
          speak english Black person
          finasteride works with my genetics
          stop listening to pol

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