Finasteride and 5AR reduce more than just DHT, like allopregnanolone, an important neurotransmitter, or dihydroprogesterone, also very important.
People that feel no difference on finasteride were mental cucks before so they claim there is no difference, but there is. Allopregnanolone even has immense potentional as an antidepressive medication, as it is depleted in that part of the population.
What makes you keep your hair amirite? Genetic failures, you never escape nature.
Its why he mentioned puberty. Those types say it doesn't do anything after puberty. Guess you're moronic.
>>dht doesn't do anything
thank you strawman
steroid branch derived from DHT
yeah anavar behaves exactly like DHT right, not like it's a heavily modified androgen that is extremely anabolic and hardly androgenic, the exact opposite of DHT
Don't think you know what a strawman is. When you use the exact same "argument" as tons of other morons, dont get mad when someone points it out.
6 months ago
Anonymous
>I am calling you out by making a strawman of the argument you’re not even making
Stop skipping brain day
Unless you crash DHT to something super low like less than 10% it won’t do anything. Finasteride can’t crush DHT low enough for that to be a problem. To do that your need dutasteride, and a good amount of it too
6 months ago
Anonymous
You mentioned puberty, meaning you subscribe to the notion that dht does nothing after puberty. Please if thats not it feel free to explain.
6 months ago
Anonymous
The only time that super high DHT is important is during puberty. Any time after that the goal is to have DHT as low as possible without getting side effects
6 months ago
Anonymous
Thank you for actually expanding. My thought, because its been the case for literally everything else science has previously said was vestigial or unneeded past a certain point, is that they just don't fully understand it yet and all evidence points to that. Whether you believe in some kind of creationism or naturalism shit just doesn't have energy/resources spent on it if it doesn't have a purpose, unless ofc theres a clinical problem.
6 months ago
Anonymous
Lets say your body naturally produces 100 units of DHT
At less than 10 units you start getting low DHT symptoms (low libido, etc.)
At above 80 units you get high DHT symptoms (hair follicle miniaturization, prostate hypertrophy, etc.)
So anything from 10-80 units is where you want to sit at
The body operates on thresholds, increasing or decreasing something by x% won't have the desired (or undesired in the case of side effects) unless it is being pushed over/below that threshold
6 months ago
Anonymous
Ty for your clarification. So you are like the one reasonable person that mentioned puberty, most of them are like this
>>dht doesn't do anything
thank you strawman
steroid branch derived from DHT
yeah anavar behaves exactly like DHT right, not like it's a heavily modified androgen that is extremely anabolic and hardly androgenic, the exact opposite of DHT
>Raises test that would be converted to DHT.
Also raises estrogen because there is more testosterone to aromatize. >Now Dht doesn't protect against the effects of estrogen. >Claims cope by saying DHT is not anabolic while it is a cns stimulant and hypertrophies type 2B fibers (the fibers that make you an explosive heavy man).
Testosterone- and DHEA-induced increases in both GLUT-4 expression and Akt and PKC-ζ/λ phosphorylations were blocked by a DHT inhibitor. Finally, the activities of phosphofructokinase and hexokinase, main glycolytic enzymes, were enhanced by testosterone or DHEA addition. These findings suggest that skeletal muscle is capable of synthesizing DHT from testosterone, and that DHT activates the glucose metabolism-related signaling pathway in skeletal muscle cells.
https://journals.physiology.org/doi/full/10.1152/ajpendo.00678.2007
Administering the 5α-reductase inhibitor in resistance-trained OLETF rats resulted in suppression of the exercise-induced effects on skeletal muscle mass, fasting glucose level, insulin sensitivity index, and GLUT-4 signaling, with a decline in muscular DHT levels. These findings suggest that resistance training-induced elevation of muscular DHT levels may contribute to improvement of hyperglycemia and skeletal muscle hypertrophy in type 2 diabetic rats.
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0165689
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3167122/
Dihydrotestosterone stimulates amino acid uptake and the expression of LAT2 in mouse skeletal muscle fibres through an ERK1/2-dependent mechanism >INB4 mouse cope >inb4 ignoring gyno cases >inb4 ignoring pfs cases >inb4 ignoring people saying they lose mass >inb4 haircafe cope
the androgenicity of testosterone for skeletal muscle performance is higher from T than DHT making Fin. superior to not taking it for gains actually anon.
all you did was show DHT affects muscles, which it does, but lacks perspective that T affects muscle more.
This is not true. Indirect and direct effects combined DHT is needed. Nature makes no mistakes. You can consider testosterone a "storage hormone" for DHT, even in muscles. It works, and after that it is quickly destroyed, not before.
Shit is so confusing. My country recently started using gender neutral pronouns and it's awful to read articles now never knowing if they are talking about a group of people or a singular person or whatever the frick.
Its in Africa moron, the Chinese guy is trying to make Africans work for projects and he is getting tired of their stupidity. Youtube has the documentary still up, maybe try "chinese man african documentary" or smth gl.
I took a standard oral dose for almost two years before taking a month off and then switching to twice-weekly very-low-dose topical applications. Haven't lost any ground, and I had gained a lot. I didn't have any negative symptoms so I can't say if this resolved anything; I just wanted to minimize systemic DHT reduction since I'll be using for years to come. During this recent period I have been gaining muscle more easily but that's likely due to the creatine I started taking around the same time I switched.
I would rather kill myself than be bald. I don’t have the head shape for it. Completely killed any sort of confidence I have. Now my hair is fuller and hairline returning.
>bald cuck trying drag down everybody else to his level
Lmao
There is literally nothing wrong with being bald.
absolutely not and I also avoid other 5-ar inhibitors like lion's mane and green tea
Any tips to avoid lion's mane ? I keep buying this SPECIFIC supplement while trying to keep my DHT intact haha silly me.
>Any tips
Read the label
I crush up 3-4 pills and put it in my minoxidil. Seems to do ok even after a cycle.
Finasteride and 5AR reduce more than just DHT, like allopregnanolone, an important neurotransmitter, or dihydroprogesterone, also very important.
People that feel no difference on finasteride were mental cucks before so they claim there is no difference, but there is. Allopregnanolone even has immense potentional as an antidepressive medication, as it is depleted in that part of the population.
What makes you keep your hair amirite? Genetic failures, you never escape nature.
Post hair, sweaty
https://en.wikipedia.org/wiki/5%CE%B1-Reductase
this is a fricking mess, thanks for the PSA
You getting psyopd into using IST baldy
>raises test
>keeps your hair
i will continue to take it thank you very much.
>raises test
at the cost of everything else
Yes I take finasteride. I am over 18 (past puberty) and am not trying to DHTmaxx
even a 70% drop in DHT (5mg/day finasteride) shouldn't cause you any problems.
>past puberty
>dht doesn't do anything! Trust the science!
>entire steroid branch derived from DHT
You can't trust the science if you can't even understand it.
Its why he mentioned puberty. Those types say it doesn't do anything after puberty. Guess you're moronic.
Don't think you know what a strawman is. When you use the exact same "argument" as tons of other morons, dont get mad when someone points it out.
>I am calling you out by making a strawman of the argument you’re not even making
Stop skipping brain day
Unless you crash DHT to something super low like less than 10% it won’t do anything. Finasteride can’t crush DHT low enough for that to be a problem. To do that your need dutasteride, and a good amount of it too
You mentioned puberty, meaning you subscribe to the notion that dht does nothing after puberty. Please if thats not it feel free to explain.
The only time that super high DHT is important is during puberty. Any time after that the goal is to have DHT as low as possible without getting side effects
Thank you for actually expanding. My thought, because its been the case for literally everything else science has previously said was vestigial or unneeded past a certain point, is that they just don't fully understand it yet and all evidence points to that. Whether you believe in some kind of creationism or naturalism shit just doesn't have energy/resources spent on it if it doesn't have a purpose, unless ofc theres a clinical problem.
Lets say your body naturally produces 100 units of DHT
At less than 10 units you start getting low DHT symptoms (low libido, etc.)
At above 80 units you get high DHT symptoms (hair follicle miniaturization, prostate hypertrophy, etc.)
So anything from 10-80 units is where you want to sit at
The body operates on thresholds, increasing or decreasing something by x% won't have the desired (or undesired in the case of side effects) unless it is being pushed over/below that threshold
Ty for your clarification. So you are like the one reasonable person that mentioned puberty, most of them are like this
>>dht doesn't do anything
thank you strawman
steroid branch derived from DHT
yeah anavar behaves exactly like DHT right, not like it's a heavily modified androgen that is extremely anabolic and hardly androgenic, the exact opposite of DHT
So be it.
>Raises test that would be converted to DHT.
Also raises estrogen because there is more testosterone to aromatize.
>Now Dht doesn't protect against the effects of estrogen.
>Claims cope by saying DHT is not anabolic while it is a cns stimulant and hypertrophies type 2B fibers (the fibers that make you an explosive heavy man).
Testosterone- and DHEA-induced increases in both GLUT-4 expression and Akt and PKC-ζ/λ phosphorylations were blocked by a DHT inhibitor. Finally, the activities of phosphofructokinase and hexokinase, main glycolytic enzymes, were enhanced by testosterone or DHEA addition. These findings suggest that skeletal muscle is capable of synthesizing DHT from testosterone, and that DHT activates the glucose metabolism-related signaling pathway in skeletal muscle cells.
https://journals.physiology.org/doi/full/10.1152/ajpendo.00678.2007
Administering the 5α-reductase inhibitor in resistance-trained OLETF rats resulted in suppression of the exercise-induced effects on skeletal muscle mass, fasting glucose level, insulin sensitivity index, and GLUT-4 signaling, with a decline in muscular DHT levels. These findings suggest that resistance training-induced elevation of muscular DHT levels may contribute to improvement of hyperglycemia and skeletal muscle hypertrophy in type 2 diabetic rats.
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0165689
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3167122/
Dihydrotestosterone stimulates amino acid uptake and the expression of LAT2 in mouse skeletal muscle fibres through an ERK1/2-dependent mechanism
>INB4 mouse cope
>inb4 ignoring gyno cases
>inb4 ignoring pfs cases
>inb4 ignoring people saying they lose mass
>inb4 haircafe cope
the androgenicity of testosterone for skeletal muscle performance is higher from T than DHT making Fin. superior to not taking it for gains actually anon.
all you did was show DHT affects muscles, which it does, but lacks perspective that T affects muscle more.
This is not true. Indirect and direct effects combined DHT is needed. Nature makes no mistakes. You can consider testosterone a "storage hormone" for DHT, even in muscles. It works, and after that it is quickly destroyed, not before.
No. I am dutasteride master race
good thread OP, you set off the trannies real hard
Ty anon I do what I can
Are transgender women women or men?
Men who are trying to turn into women
(It doesn't work despite the metabolic horrors unleashed upon them by the israelite)
Shit is so confusing. My country recently started using gender neutral pronouns and it's awful to read articles now never knowing if they are talking about a group of people or a singular person or whatever the frick.
Lmao what meme country is this
Its in Africa moron, the Chinese guy is trying to make Africans work for projects and he is getting tired of their stupidity. Youtube has the documentary still up, maybe try "chinese man african documentary" or smth gl.
thank you for the (you)
Lil lil zoomies, it's okay to take finasteride.
Just don't forget to add she/her to your socials too LMAO
I took a standard oral dose for almost two years before taking a month off and then switching to twice-weekly very-low-dose topical applications. Haven't lost any ground, and I had gained a lot. I didn't have any negative symptoms so I can't say if this resolved anything; I just wanted to minimize systemic DHT reduction since I'll be using for years to come. During this recent period I have been gaining muscle more easily but that's likely due to the creatine I started taking around the same time I switched.
I would rather kill myself than be bald. I don’t have the head shape for it. Completely killed any sort of confidence I have. Now my hair is fuller and hairline returning.
>trans commie Webster as a source
DHT DOES NOTHING IN ADULTHOOD WHO GIVES A FRICK
>source: Globohomo.org
Who here is a psyop lmao